Zhao Y, Bai L, Zhang Y, Yao R, Solar Y, Cling R, Chen X, Wang H, Yao X, Xiao Y, et al. Kind I collagen adorned nanoporous community on titanium implant floor promotes osseointegration via mediating immunomodulation, angiogenesis, and osteogenesis. Biomaterials. 2022;288:121684.
Li J, Zhao C, Xu Y, Tune L, Chen Y, Xu Y, Ma Y, Wang S, Xu A, He F. Transforming of the osteoimmune microenvironment after biomaterials implantation in murine tibia: single-cell transcriptome evaluation. Bioact Mater. 2023;22:404–22.
Batool F, Özçelik H, Stutz C, Gegout PY, Benkirane-Jessel N, Petit C, Huck O. Modulation of immune-inflammatory responses via floor modifications of biomaterials to advertise bone therapeutic and regeneration. J Tissue Eng. 2021;12:20417314211041428.
Newman H, Shih YV, Varghese S. Decision of irritation in bone regeneration. From understandings to therapeutic purposes. Biomaterials. 2021;277:121114.
Walsh MC, Kim N, Kadono Y, Rho J, Lee SY, Lorenzo J, Choi Y. Osteoimmunology. Interaction between the immune system and bone metabolism. Annu Rev Immunol. 2006;24:33–63.
Walsh MC, Takegahara N, Kim H, Choi Y. Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity. Nat Rev Rheumatol. 2018;14:146–56.
Wang X, Wang H, Zhang T, Cai L, Kong C, He J. Present Information Relating to the Interplay Between Oral Bone Metabolic Problems and Diabetes Mellitus. Entrance Endocrinol. 2020;11.
de Oliveira P, Bonfante EA, Bergamo ETP, de Souza SLS, Riella L, Torroni A, Benalcazar Jalkh EB, Witek L, Lopez CD, Zambuzzi WF, et al. Weight problems/Metabolic syndrome and diabetes Mellitus on Peri-implantitis. Developments Endocrinol Metab. 2020;31:596–610.
Gibon E, Lu LY, Nathan Ok, Goodman SB. Irritation, ageing, and bone regeneration. J Orthop Translat. 2017;10:28–35.
Dereka X, Calciolari E, Donos N, Mardas N. Osseointegration in osteoporotic-like situation: a scientific assessment of preclinical research. J Periodontal Res. 2018;53:933–40.
Wang W, Xiong Y, Zhao R, Li X, Jia W. A novel hierarchical biofunctionalized 3D-printed porous Ti6Al4V scaffold with enhanced osteoporotic osseointegration via osteoimmunomodulation. J Nanobiotechnol. 2022;20:68.
Shen Y, Zhang Y, Zhou Z, Wang J, Han D, Solar J, Chen G, Tang Q, Solar W, Chen L. Dysfunction of macrophages results in diabetic bone regeneration deficiency. Entrance Immunol. 2022;13.
Fan L, Guan P, Xiao C, Wen H, Wang Q, Liu C, Luo Y, Ma L, Tan G, Yu P, et al. Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration. Bioact Mater. 2021;6:2754–66.
Lee J, Byun H, Madhurakkat Perikamana SK, Lee S, Shin H. Present advances in Immunomodulatory Biomaterials for Bone Regeneration. Adv Healthc Mater. 2019;8:e1801106.
Chen Z, Bachhuka A, Han S, Wei F, Lu S, Visalakshan RM, Vasilev Ok, Xiao Y. Tuning Chemistry and Topography of Nanoengineered Surfaces to control Immune response for bone regeneration purposes. ACS Nano. 2017;11:4494–506.
Ni S, Zhai D, Huan Z, Zhang T, Chang J, Wu C. Nanosized concave pit/convex dot microarray for immunomodulatory osteogenesis and angiogenesis. Nanoscale. 2020;12:16474–88.
Chen Z, Bachhuka A, Wei F, Wang X, Liu G, Vasilev Ok, Xiao Y. Nanotopography-based technique for the exact manipulation of osteoimmunomodulation in bone regeneration. Nanoscale. 2017;9:18129–52.
Pajarinen J, Lin T, Gibon E, Kohno Y, Maruyama M, Nathan Ok, Lu L, Yao Z, Goodman SB. Mesenchymal stem cell-macrophage crosstalk and bone therapeutic. Biomaterials. 2019;196:80–9.
Michalski MN, McCauley LK. Macrophages and skeletal well being. Pharmacol Ther. 2017;174:43–54.
Christo SN, Bachhuka A, Diener KR, Mierczynska A, Hayball JD, Vasilev Ok. The function of Floor Nanotopography and Chemistry on Main Neutrophil and Macrophage Mobile responses. Adv Healthc Mater. 2016;5:956–65.
Atcha H, Jairaman A, Holt JR, Meli VS, Nagalla RR, Veerasubramanian PK, Brumm KT, Lim HE, Othy S, Cahalan MD, et al. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing. Nat Commun. 2021;12:3256.
Jain N, Moeller J, Vogel V. Mechanobiology of Macrophages: how bodily components coregulate macrophage plasticity and phagocytosis. Annu Rev Biomed Eng. 2019;21:267–97.
Meli VS, Atcha H, Veerasubramanian PK, Nagalla RR, Luu TU, Chen EY, Guerrero-Juarez CF, Yamaga Ok, Pandori W, Hsieh JY et al. YAP-mediated mechanotransduction tunes the macrophage inflammatory response. Sci Adv. 2020;6.
Jain N, Vogel V. Spatial confinement downsizes the inflammatory response of macrophages. Nat Mater. 2018;17:1134–44.
Hansel CS, Crowder SW, Cooper S, Gopal S, João Pardelha da Cruz M, de Oliveira Martins L, Keller D, Rothery S, Becce M, Cass AEG, et al. Nanoneedle-mediated stimulation of Cell Mechanotransduction Equipment. ACS Nano. 2019;13:2913–26.
Carthew J, Abdelmaksoud HH, Hodgson-Garms M, Aslanoglou S, Ghavamian S, Elnathan R, Spatz JP, Brugger J, Thissen H, Voelcker NH, et al. Precision Floor Microtopography regulates cell destiny by way of adjustments to Actomyosin Contractility and Nuclear Structure. Adv Sci (Weinh). 2021;8:2003186.
Janota CS, Calero-Cuenca FJ, Gomes ER. The function of the cell nucleus in mechanotransduction. Curr Opin Cell Biol. 2020;63:204–11.
Swift J, Ivanovska IL, Buxboim A, Harada T, Dingal PC, Pinter J, Pajerowski JD, Spinler KR, Shin JW, Tewari M, et al. Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation. Science. 2013;341:1240104.
Shiu JY, Aires L, Lin Z, Vogel V. Nanopillar pressure measurements reveal actin-cap-mediated YAP mechanotransduction. Nat Cell Biol. 2018;20:262–71.
Saez A, Herrero-Fernandez B, Gomez-Bris R, Somovilla-Crespo B, Rius C, Gonzalez-Granado JM. Lamin A/C and the Immune System: One Intermediate Filament, Many Faces. Int J Mol Sci. 2020;21.
Toribio-Fernández R, Zorita V, Rocha-Perugini V, Iborra S, Martínez Del Hoyo G, Chevre R, Dorado B, Sancho D, Sanchez-Madrid F, Andrés V, et al. Lamin A/C augments Th1 differentiation and response towards vaccinia virus and Leishmania main. Cell Demise Dis. 2018;9:9.
Toribio-Fernández R, Herrero-Fernandez B, Zorita V, López JA, Vázquez J, Criado G, Pablos JL, Collas P, Sánchez-Madrid F, Andrés V, et al. Lamin A/C deficiency in CD4(+) T-cells enhances regulatory T-cells and prevents inflammatory bowel illness. J Pathol. 2019;249:509–22.
Buxboim A, Swift J, Irianto J, Spinler KR, Dingal PC, Athirasala A, Kao YR, Cho S, Harada T, Shin JW, et al. Matrix elasticity regulates lamin-A,C phosphorylation and turnover with suggestions to actomyosin. Curr Biol. 2014;24:1909–17.
Chen L, Jiang F, Qiao Y, Li H, Wei Z, Huang T, Lan J, Xia Y, Li J. Nucleoskeletal stiffness regulates stem cell migration and differentiation via lamin A/C. J Cell Physiol. 2018;233:5112–8.
González-Granado JM, Silvestre-Roig C, Rocha-Perugini V, Trigueros-Motos L, Cibrián D, Morlino G, Blanco-Berrocal M, Osorio FG, Freije JMP, López-Otín C, et al. Nuclear envelope lamin-A {couples} actin dynamics with immunological synapse structure and T cell activation. Sci Sign. 2014;7:ra37.
Rocha-Perugini V, González-Granado JM. Nuclear envelope lamin-A as a coordinator of T cell activation. Nucleus. 2014;5:396–401.
Kim Y, Bayona PW, Kim M, Chang J, Hong S, Park Y, Budiman A, Kim YJ, Choi CY, Kim WS, et al. Macrophage lamin A/C regulates irritation and the event of Weight problems-Induced insulin resistance. Entrance Immunol. 2018;9:696.
Wang J, Meng F, Tune W, Jin J, Ma Q, Fei D, Fang L, Chen L, Wang Q, Zhang Y. Nanostructured titanium regulates osseointegration by way of influencing macrophage polarization within the osteogenic surroundings. Int J Nanomedicine. 2018;13:4029–43.
Zhang H, Cooper LF, Zhang X, Zhang Y, Deng F, Tune J, Yang S. Titanium nanotubes induce osteogenic differentiation via the FAK/RhoA/YAP cascade. RSC Adv. 2016;6:44062–9.
Zhang H, Yang S, Masako N, Lee DJ, Cooper LF, Ko CC. Proliferation of preosteoblasts on TiO2 nanotubes is FAK/RhoA associated. RSC Adv. 2015;5:38117–24.
Soleimani M, Nadri S. A protocol for isolation and tradition of mesenchymal stem cells from mouse bone marrow. Nat Protoc. 2009;4:102–6.
Kim J-Y, Park S-H, Baek JM, Erkhembaatar M, Kim MS, Yoon Ok-H, Oh J, Lee MS. Harpagoside inhibits RANKL-Induced Osteoclastogenesis by way of Syk-Btk-PLCγ2-Ca2 + signaling pathway and prevents inflammation-mediated bone loss. J Nat Prod. 2015;78:2167–74.
Wu H, Hu B, Zhou X, Zhou C, Meng J, Yang Y, Zhao X, Shi Z, Yan S. Artemether attenuates LPS-induced inflammatory bone loss by inhibiting osteoclastogenesis and bone resorption by way of suppression of MAPK signaling pathway. Cell Demise Dis. 2018;9:498.
Ihalainen TO, Aires L, Herzog FA, Schwartlander R, Moeller J, Vogel V. Differential basal-to-apical accessibility of lamin A/C epitopes within the nuclear lamina regulated by adjustments in cytoskeletal pressure. Nat Mater. 2015;14:1252–61.
Jain N, Iyer KV, Kumar A, Shivashankar GV. Cell geometric constraints induce modular gene-expression patterns by way of redistribution of HDAC3 regulated by actomyosin contractility. Proc Natl Acad Sci U S A. 2013;110:11349–54.
Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human getting older. Science. 2006;312:1059–63.
Zonderland J, Moldero IL, Anand S, Mota C, Moroni L. Dimensionality adjustments actin community via lamin A/C and zyxin. Biomaterials. 2020;240:119854.
Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima Ok, Stewart CL, Burke B. Lack of A-type lamin expression compromises nuclear envelope integrity resulting in muscular dystrophy. J Cell Biol. 1999;147:913–20.
Tang Y, Zhu L, Cho JS, Li XY, Weiss SJ. Matrix reworking controls a nuclear lamin A/C-emerin community that directs wnt-regulated stem cell destiny. Dev Cell. 2022;57:480–495e486.
Ho CY, Jaalouk DE, Vartiainen MK, Lammerding J. Lamin A/C and emerin regulate MKL1-SRF exercise by modulating actin dynamics. Nature. 2013;497:507–11.
Huang J, Li R, Yang J, Cai M, Lee Y, Wang A, Cheng B, Wang Y. Bioadaptation of implants to in vitro and in vivo oxidative stress pathological situations by way of nanotopography-induced FoxO1 signaling pathways to reinforce Osteoimmunal regeneration. Bioact Mater. 2021;6:3164–76.
Yang Y, Hu H, Zeng M, Chu H, Gan Z, Duan J, Rong M. The survival charges and danger components of implants within the early stage: a retrospective examine. BMC Oral Well being. 2021;21:293.
Darby I. Danger components for periodontitis & peri-implantitis. Periodontol 2000. 2022;90:9–12.
He Q, Yuan S, Tang H, Wang S, Mu Z, Li D, Wang S, Jing X, Hu S, Ji P, et al. Safeguarding Osteointegration in Diabetic Sufferers: a potent “Chain Armor” Coating for scavenging ROS and macrophage reprogramming in a microenvironment-responsive method. Adv Funct Mater. 2021;31:2101611.
Zheng Y, Gao A, Bai J, Liao Q, Wu Y, Zhang W, Guan M, Tong L, Geng D, Zhao X, et al. A programmed floor on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to realize ameliorative osseointegration beneath osteoporotic situations. Bioact Mater. 2022;14:364–76.
Dai X, Bai Y, Heng BC, Li Y, Tang Z, Lin C, Liu O, He Y, Zhang X, Deng X. Biomimetic hierarchical implant surfaces promote early osseointegration in osteoporotic rats by suppressing macrophage activation and osteoclastogenesis. J Mater Chem B. 2022;10:1875–85.
Alghamdi HS, Jansen JA. The event and way forward for dental implants. Dent Mater J. 2020;39:167–72.
Donnaloja F, Carnevali F, Jacchetti E, Raimondi MT. Lamin A/C Mechanotransduction in Laminopathies. Cells. 2020;9.
Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH. Nuclear lamin A/C harnesses the perinuclear apical actin cables to guard nuclear morphology. Nat Commun. 2017;8:2123.
Holaska JM, Kowalski AK, Wilson KL. Emerin caps the pointed finish of actin filaments. Proof for an actin cortical community on the nuclear internal membrane. PLoS Biol. 2004;2:E231.
