With its lengthy scientific historical past, conventional Chinese language medication (TCM) has gained acceptance for its particular efficacy and security within the remedy of a number of illnesses. Nano-sized supplies examine of Chinese language natural medicines (CHMs) is resulting in an elevated understanding of assessing TCM therapies, which can be a promising technique to illustrate the fabric foundation of CHMs by way of the processing and extraction of it. On this overview, we offer an outline of the nanostructures of pure and engineered CHMs, together with extracted CHMs, polymer nanoparticles, liposomes, micelles, and nanofibers. Subsequently, the purposes of those CHMs-derived nanostructures to explicit illnesses are summarized and mentioned. Moreover, we talk about some great benefits of these nanostructures for finding out CHMs therapeutic efficacy. Lastly, the important thing challenges and alternatives for the event of those nanostructures are outlined.