Summary
Bilirubin is a key biomarker within the analysis of jaundice. Herein, we proposed a easy and handy quantitative methodology for the fluorescent detection of bilirubin. We developed a copper nanoclusters coated by zinc-based metal-organic frameworks (Cu NCs@MOF). The ready Cu NCs@MOF exhibited brilliant blue fluorescence excited with ultra-violet mild and nicely stability at varied environments. Extra importantly, Cu NCs@MOF was used for bilirubin detection primarily based on the rising crimson fluorescence emission peak induced by bilirubin. Moreover, Cu NCs@MOF have been made into check strip for the visible detection of bilirubin by the fluorescence coloration variation.
Disclosure assertion
The authors declare no competing monetary curiosity.
Scheme 1. The illustration of the preparation means of ZIF8@Cu NCs and the detection for BR.
Scheme 1. The illustration of the preparation means of ZIF8@Cu NCs and the detection for BR.
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