A challenge aiming to develop a novel bioinspired membrane to selectively extract compounds from water has gained a €3m grant from the European Innovation Council (EIC) Pathfinder programme.
BIOMEM is a consortium led by Danish biotech firm Aquaporin, with analysis led by Aston College’s Dr Alan Goddard.
Present water filtration applied sciences require excessive stress and vitality inputs and usually are not selective in regards to the molecules they filter. BIOmimetic selective extraction MEMbranes (BIOMEM) will be capable to completely extract single compounds from aqueous options and can use 50-75% much less vitality than present state-of-the-art nanofiltration applied sciences. They may be capable to work even at low focus of the goal molecule.
The membranes have the potential for use in numerous sectors together with wastewater remedy, for instance to take away explicit pollution comparable to phosphate, and in biotechnology to extract helpful merchandise from fermentation broth, comparable to nutritional vitamins and prescription drugs. The BIOMEM researchers consider that their know-how shall be game-changing for bioprocessing industries, because the membranes will drastically cut back processing prices.
BIOMEM represents the primary important award to the newly based Aston Institute for Membrane Excellence (AIME), combining the areas of membrane protein biochemistry and polymer science to create an revolutionary answer to international challenges.
The phrase ‘biomimetic’ means mimicking biology, and the brand new membranes will mimic pure cell membranes. Cell membranes have particular transport proteins embedded inside them to maneuver explicit substances, comparable to steel ions and sugars, out and in of the cell. The BIOMEM consortium will take transport proteins from organic cell membranes and embed them in additional sturdy, industrial plastic membranes to create extraordinarily selective separation membranes.
Dr Goddard and the interdisciplinary group at Aston College, which additionally consists of Dr Alice Rothnie and Professor Roslyn Invoice from the College of Biosciences, and Dr Matthew Derry, Professor Brian Tighe and Professor Paul Topham from the College of Engineering and Bodily Sciences, will generate and take a look at novel polymers able to extracting transport proteins and their stabilising lipids from organic membranes, while retaining their exercise.
Membrane transport proteins are usually unstable and due to this fact tough to isolate and examine. With the stabilised, extracted proteins from Aston College, the remainder of the consortium will be capable to assemble the brand new bioinspired membranes and characterise them to know their organisation and performance. This may enable them to design and optimise membranes for customized goal compounds.
The consortium will take a look at the membranes they produce in proof-of-concept experiments to extract complicated, high-value meals elements from fermentation broth and phosphate from wastewater. Finally, the companions purpose to provide ‘plug and play’ bespoke selective membranes.
The BIOMEM consortium additionally consists of the French Nationwide Centre for Scientific Analysis (Centre nationwide de la recherche scientifique (CNRS)), Copenhagen College in Denmark, Tampere College in Finland and dsm-firmenich, a worldwide science and innovation chief in diet, well being and wonder.
Dr Goddard mentioned:
“That is an extremely thrilling alternative to essentially redefine how industrial separation membranes are made and to create a platform system that can be utilized throughout an entire vary of sectors. Our consortium has representatives from all phases of membrane manufacturing, together with industrial companions, to make sure we give attention to real-world relevance and software.”
Torsten Bak, Senior Vice President of the Aquaporin Deep Tech Middle and chief of the challenge at Aquaporin, mentioned:
“We’re thrilled to announce the BIOMEM challenge and stay up for working with the consortium. The profitable funding from the Pathfinder programme now positions us to start a long-anticipated challenge to develop a novel biomembrane with distinctive properties which have the potential to optimise numerous industries.”
