Uhlén, M. et al. Tissue-based map of the human proteome. Science 347, 1260419–1260419 (2015).
Miwa, H., Dimatteo, R., de Rutte, J., Ghosh, R. & Di Carlo, D. Single-cell sorting based mostly on secreted merchandise for functionally outlined cell therapies. Microsyst. Nanoeng. 8, 84 (2022).
Levy, O. et al. Shattering boundaries towards clinically significant MSC therapies. Sci. Adv. 6, eaba6884 (2020).
Kode, J. A., Mukherjee, S., Joglekar, M. V. & Hardikar, A. A. Mesenchymal stem cells: immunobiology and position in immunomodulation and tissue regeneration. Cytotherapy 11, 377–391 (2009).
Bode, D., Cull, A. H., Rubio-Lara, J. A. & Kent, D. G. Exploiting single-cell instruments in gene and cell remedy. Entrance. Immunol. 12, 2775 (2021).
Lee, S., De Rutte, J., Dimatteo, R., Koo, D. & Di Carlo, D. Scalable fabrication and use of 3D structured microparticles spatially functionalized with biomolecules. ACS Nano 16, 38–49 (2022).
De Rutte, J. et al. Suspendable hydrogel nanovials for massively parallel single-cell practical evaluation and sorting. ACS Nano 16, 7242–7257 (2022).
de Rutte, J., Dimatteo, R., Zhu, S., Archang, M. M. & Di Carlo, D. Sorting single-cell microcarriers utilizing industrial circulation cytometers. SLAS Technol. 27, 150–159 (2022).
Stoeckius, M. et al. Simultaneous epitope and transcriptome measurement in single cells. Nat. Strategies 14, 865–868 (2017).
Peterson, V. M. et al. Multiplexed quantification of proteins and transcripts in single cells. Nat. Biotechnol. 35, 936–939 (2017).
Thej, C., Ramadasse, B., Walvekar, A., Majumdar, A. S. & Balasubramanian, S. Growth of a surrogate efficiency assay to find out the angiogenic exercise of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product. Stem Cell. Res. Ther. 8, 1–14 (2017).
Berry, J. D. et al. NurOwn, section 2, randomized, medical trial in sufferers with ALS. Neurology 93, e2294–e2305 (2019).
Yousefi, Okay. et al. The design and rationale of a section 2b, randomized, double-blinded, and placebo-controlled trial to guage the security and efficacy of lomecel-B in older adults with frailty. J. Frailty Getting old 11, 214–223 (2022).
Mereu, E. et al. Benchmarking single-cell RNA-sequencing protocols for cell atlas initiatives. Nat. Biotechnol. 38, 747–755 (2020).
Koch, F. et al. Generic technique of printing window adjustment for extrusion-based 3D-bioprinting to keep up excessive viability of mesenchymal stem cells in an alginate-gelatin hydrogel. Bioprinting 20, e00094 (2020).
Schwartz, M. A. & Assoian, R. Okay. Integrins and cell proliferationregulation of cyclin-dependent kinases through cytoplasmic signaling pathways. J. Cell Sci. 114, 2553–2560 (2001).
Potier, E. et al. Hypoxia impacts mesenchymal stromal cell osteogenic differentiation and angiogenic issue expression. Bone 40, 1078–1087 (2007).
Liu, G.-S. et al. Pharmacological priming of adipose-derived stem cells for paracrine VEGF manufacturing with deferoxamine. J. Tissue Eng. Regen. Med. 10, E167–E176 (2016).
Waters, J. A., Urbano, I., Robinson, M. & Home, C. D. Insulin-like progress issue binding protein 5: various roles in most cancers. Entrance. Oncol. 12, 1052457 (2022).
Sureshbabu, A. et al. IGFBP5 induces cell adhesion, will increase cell survival and inhibits cell migration in MCF-7 human breast most cancers cells. J. Cell Sci. 125, 1693–1705 (2012).
Al Halawani, A., Abdulkhalek, L., Mithieux, S. M. & Weiss, A. S. Tropoelastin promotes the formation of dense, interconnected endothelial networks. Biomolecules 11, 1318 (2021).
Zheng, H., Fu, G., Dai, T. & Huang, H. Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 through PI3K/Akt/eNOS sign transduction pathway. J. Cardiovasc. Pharmacol. 50, 274–280 (2007).
Chou, C. H. et al. SCUBE3 regulation of early lung most cancers angiogenesis and metastatic development. Clin. Exp. Metastasis 30, 741–752 (2013).
Fan, D. & Kassiri, Z. Biology of tissue inhibitor of metalloproteinase 3 (TIMP3), and its therapeutic implications in cardiovascular pathology. Entrance. Physiol. 11, 661 (2020).
Poss, Okay. D. & Tonegawa, S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl Acad. Sci. USA 94, 10919 (1997).
Lenselink, E. A. Position of fibronectin in regular wound therapeutic. Int. Wound J. 12, 313 (2015).
DiFeo, A., Martignetti, J. A. & Narla, G. The position of KLF6 and its splice variants in most cancers remedy. Drug Resist. Updat. 12, 1–7 (2009).
Higuchi, M. et al. PRRX1- and PRRX2-positive mesenchymal stem/progenitor cells are concerned in vasculogenesis throughout rat embryonic pituitary improvement. Cell Tissue Res. 361, 557–565 (2015).
Dong, Y. et al. RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation throughout skeletal improvement. Growth 137, 1461–1471 (2010).
Han, H. et al. TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions. Nucleic Acids Res. 46, D380–D386 (2018).
Cheng, R. Y.-H. et al. SEC-seq: affiliation of molecular signatures with antibody secretion in hundreds of single human plasma cells. Nat. Commun. 14, 3567 (2023).
Shum, E. Y., Walczak, E. M., Chang, C. & Christina Fan, H. Quantitation of mRNA transcripts and proteins utilizing the BD RhapsodyTM single-cell evaluation system. Adv. Exp. Med. Biol. 1129, 63–79 (2019).
Trzupek, D. et al. Discovery of CD80 and CD86 as current activation markers on regulatory T cells by protein-RNA single-cell evaluation. Genome Med. 12, 55 (2020).
Vanuytsel, Okay. et al. Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment. Nat. Commun. 13, 1103 (2022).
Wu, T. et al. Time-resolved evaluation of single-cell protein secretion by sequencing. Nat. Strategies 20, 723–734 (2023).
Xie, Z. et al. Single-cell RNA sequencing evaluation of human bone-marrow-derived mesenchymal stem cells and practical subpopulation identification. Exp. Mol. Med. 54, 483–492 (2022).
Solar, C. et al. Single-cell RNA-seq highlights heterogeneity in human major Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro. Stem Cell Res. Ther. 11, 149 (2020).
Zhang, C. et al. Single-cell transcriptomic evaluation reveals the mobile heterogeneity of mesenchymal stem cells. Genomics Proteom. Bioinform. 20, 70–86 (2022).
Cui, Y. et al. Single-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capability. Int. J. Oral. Sci. 13, 44 (2021).
Vistain, L. et al. Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing. Nat. Strategies 19, 1578–1589 (2022).
Baloh, R. H. et al. Transplantation of human neural progenitor cells secreting GDNF into the spinal twine of sufferers with ALS: a section 1/2a trial. Nat. Med. 28, 1813–1822 (2022).
Carraro, G. et al. Transcriptional evaluation of cystic fibrosis airways at single-cell decision reveals altered epithelial cell states and composition. Nat. Med. 27, 806–814 (2021).
Chen, G. et al. Complete identification and characterization of human secretome based mostly on integrative proteomic and transcriptomic information. Entrance. Cell Dev. Biol. 7, 299 (2019).
Hu, H. et al. AnimalTFDB 3.0: a complete useful resource for annotation and prediction of animal transcription elements. Nucleic Acids Res. 47, D33–D38 (2019).
Bausch-Fluck, D. et al. The in silico human surfaceome. Proc. Natl Acad. Sci. USA 115, E10988–E10997 (2018).
